Publications Publications – NSF iBioFoundry UIUC Publications Design of Biochemical Pathways via AI/ML-Enabled Retrobiosynthesis H. Li, X. Liu, H. Zhao Wiley-VCH (2025) Read Article Enzyme Property Prediction Using Artificial Intelligence L. Yuan, S. Shafaei, H. Zhao Current Opinion in Chemical Engineering (2025) Read Article Biofoundries: Principles, Tools, and Applications N. Singh, J. Chen, J. Lu, A. Sharma, W. Harrison, Z. Zhu, H. Zhao Elsevier – Reference Module in Life Sciences (2025) Read Article Open Enzyme Database: A Community-Wide Repository for Sharing Enzyme Data L. Yuan, D. Bianchi, K. Arneson, B. Guo, S. Lambert, C. Stephens, Y. Wasnik, C. Pond, M. Berry, H. Zhao Nucleic Acids Research (2025) Read Article Artificial Intelligence–Powered Biofoundries for Protein Engineering and Metabolic Engineering J. Chen, N. Singh, J. Lu, S. Lane, H. Zhao Current Opinion in Biotechnology (2025) Read Article A Generalized Platform for Artificial Intelligence-Powered Autonomous Enzyme Engineering N. Singh, S. Lane, T. Yu, J. Lu, A. Ramos, H. Cui, H. Zhao Nature Communications (2025) Read Article Enhancing Lipid Production in Plant Cells Through Automated High-Throughput Genome Editing and Phenotyping J. Dong, S. Croslow, S. Lane, D. Castro, J. Blanford, S. Zhou, K. Park, S. Burgess, M. Root, E. Cahoon, J. Shanklin, J. Sweedler, H. Zhao, M. Hudson The Plant Cell (2025) Read Article Self-Resistance-Gene-Guided, High-Throughput Automated Genome Mining of Bioactive Natural Products from Streptomyces Y. Yuan, C. Huang, N. Singh, G. Xun, H. Zhao Cell Systems (2025) Read Article CRISPR-COPIES: An In Silico Platform for Discovery of Neutral Integration Sites for CRISPR/Cas-Facilitated Gene Integration A. Boob, Z. Zhu, P. Intasian, M. Jain, V. Petrov, S. Lane, S. Tan, G. Xun, H. Zhao Nucleic Acids Research (2024) Read Article In Vitro Continuous Protein Evolution Empowered by Machine Learning and Automation T. Yu, A. Boob, N. Singh, Y. Su, H. Zhao Cell Systems (2023) Read Article A Scalable Platform to Discover Antimicrobials of Ribosomal Origin R. S. Ayikpoe, C. Shi, A. J. Battiste, et al. Nature Communications (2022) Read Article PlasmidMaker is a Versatile, Automated, and High Throughput End-to-End Platform for Plasmid Construction B. Enghiad, P. Xue, N. Singh, A. Boob, C. Shi, V. Petrov, R. Liu, S. Peri, S. Lane, E. Gaither, H. Zhao Nature Communications (2022) Read Article Biosystems Design by Directed Evolution Y. Wang, X. Yu, H. Zhao AIChE Journal (2019) Read Article Building a Global Alliance of Biofoundries N. Hillson, M. Caddick, Y. Cai, J. A. Carrasco, et al. Nature Communications (2019) Read Article Towards a Fully Automated Algorithm Driven Platform for Biosystems Design M. HamediRad, R. Chao, S. Weisberg, J. Lian, S. Sinha, H. Zhao Nature Communications (2019) Read Article Engineering Biological Systems Using Automated Biofoundries R. Chao, S. Mishra, T. Si, H. Zhao Metabolic Engineering (2017) Read Article Automated Multiplex Genome-Scale Engineering in Yeast T. Si, R. Chao, Y. Min, Y. Wu, W. Ren, H. Zhao Nature Communications (2017) Read Article Fully Automated One-Step Synthesis of Single-Transcript TALEN Pairs Using a Biological Foundry R. Chao, J. Liang, I. Tasan, T. Si, L. Ju, H. Zhao ACS Synthetic Biology (2017) Read Article No publications match your search.